How to apply
Read the full announcement on Grants.gov before you start. Federal applications are submitted through Grants.gov (or the agency's own system) and require a Unique Entity ID from SAM.gov. Registration can take several weeks, so start early.
What are the odds for a first-time applicant?
Mostly repeat grantees: only 5% of awards go to new applicants. Apply with a strong track record or a partner who has won before. Based on 2,132 new awards in FY2023–25. Organizations under $1M in revenue won 0% of the awards that went to nonprofits. The median award is $694,974. Expect about 251 days between posting and deadline.
Who can apply for Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)?
See the official announcement for eligibility details.
When is the deadline?
Applications are due Jan 7, 2028. Always confirm the time and time zone in the official announcement.