Federal · RFA-NS-27-007 · ALN 93.395, 93.866, 93.839

HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)

National Institutes of Health · HHS

This opportunity is not listed as open to nonprofits. Check the eligible applicants below before you apply.

Your odds: program 93.395

A realistic target for an established nonprofit. 12% of awards go to first-time applicants and nonprofits win 22%.

Based on 1,360 new awards in FY2023–25. Organizations under $1M in revenue won 0% of the awards that went to nonprofits. The median award is $927,200. Expect about 180 days between posting and deadline.

First-time winners
12%
of new 93.395 awards
Nonprofit share
22%
of awards
Median award
$927K
FY2025
New awards, FY2025
395
1,360 in 3 years
Typical window
180 d
usually posts Dec
Under-$1M orgs
0%
of nonprofit awards

Full history for 93.395 Cancer Treatment Research: past winners, past rounds, where the money goes

Deadline
Feb 20, 2029
Posted
Jun 16, 2026
Cost sharing
Not required

How to apply

Read the full announcement on Grants.gov before you start. Federal applications are submitted through Grants.gov (or the agency's own system) and require a Unique Entity ID from SAM.gov. Registration can take several weeks, so start early.

View on Grants.gov

What are the odds for a first-time applicant?

A realistic target for an established nonprofit. 12% of awards go to first-time applicants and nonprofits win 22%. Based on 1,360 new awards in FY2023–25. Organizations under $1M in revenue won 0% of the awards that went to nonprofits. The median award is $927,200. Expect about 180 days between posting and deadline.

Who can apply for HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)?

See the official announcement for eligibility details.

When is the deadline?

Applications are due Feb 20, 2029. Always confirm the time and time zone in the official announcement.

Email me matching grants