About this grant
The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to solicit new, renewal, and competing revision applications, and their resubmissions, for research project cooperative agreements. The proposed research must be relevant to the mission of NIA. Areas of research that fall within NIA’s mission include: genetic, biological, neuroscientific, preclinical, clinical, behavioral, social, psychological, and economic research on aging and the health and well-being of older people. This includes research to understand the nature of aging and the aging process, research on diseases and conditions associated with aging, and other special problems and needs associated with growing older, in order to extend the healthy, active years of life. NIA places major emphasis on, and has substantial resources for, research on Alzheimer's disease (AD) and Alzheimer's disease-related dementias (ADRD). ADRDs include Frontotemporal dementia, vascular contributions to cognitive impairment and dementia, Lewy body dementias, and multiple etiology dementias based on similarities in clinical symptoms and brain pathologies between these and pathologic AD and/or clinical AD. The NOFO intends to utilize the U01 activity code. The U01 activity code requires substantial programmatic involvement in order to execute the research. This includes, but is not limited to, the following: establishing milestone plans, access to various NIH resources, collaborative activities of a consortium, the development of working groups and/or coordinating committees, and the formation of an External Scientific Panel. Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Prospective applicants are strongly encouraged to contact NIA program staff prior to submitting an application to discuss the responsiveness of their proposed research to the NOFO and its relevance to NIA’s programmatic priorities.
Who can apply
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
What it funds
How to apply
Read the full announcement on Grants.gov before you start. Federal applications are submitted through Grants.gov (or the agency's own system) and require a Unique Entity ID from SAM.gov. Registration can take several weeks, so start early. Contact: NIA Scientific Contact · NIA-NOFO-Scientific@nih.gov · Please contact via e-mail
What are the odds for a first-time applicant?
Mostly repeat grantees: only 6% of awards go to new applicants. Apply with a strong track record or a partner who has won before. Based on 3,380 new awards in FY2023–25. Organizations under $1M in revenue won 1% of the awards that went to nonprofits. The median award is $506,031. Expect about 159 days between posting and deadline.
Who can apply for Research Project Cooperative Agreements in Aging and/or Alzheimer's disease (AD) and Alzheimer's disease-related dementias (ADRD) Research?
Eligible applicants: Others (see eligibility text); City or township governments; Nonprofits without 501(c)(3) status; Public & state-controlled colleges; 501(c)(3) nonprofits; Federally recognized tribal governments; Native American tribal organizations; County governments; Small businesses; Independent school districts; State governments; Public & Indian housing authorities; Special district governments; For-profit organizations; Private colleges & universities. Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
When is the deadline?
Applications are due Jun 20, 2026 (this deadline has passed). Always confirm the time and time zone in the official announcement.
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