About this grant
The Office of Data Science Strategy (ODSS) along with other NIH Institutes and Centers NEI, NHLBI, NHGRI, NIA, NIAAA, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIMH, NINDS, NIMHD, NLM, NCCIH, and NCI intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for renewal of the funding opportunity for Building Sustainable Software Tools for Open Science (RFA-OD-24-010). This funding opportunity is intended to provide a flexible mechanism to support the use of best practices and design principles for scientific software development/engineering and to promote community engagement for open science. Successful grants will enable and/or enhance biomedical, clinical, behavioral, social, and health-related research endeavors by (1) developing robust, sustainable, scalable, and reproducible research software tools and workflows, (2) extending the impact of research software by broader dissemination to the scientific community, (3) supporting collaborations between scientists and software engineers to leverage modern, best practices in research software development, and (4) enhancing software skills of the research workforce. This initiative is aligned with the NIH Strategic Plan for Data Science , which describes actions aimed at building a better data infrastructure and a modernized data ecosystem. No applications are being solicited at this time. Given the early expiration of RFA-OD-24-010, this notice will allow for potential applicants the opportunity to continue developing high-impact research software projects. Investigators with expertise and insights into this area of research software development are encouraged to consider applying for this new NOFO that will use the R03 activity code.
Who can apply
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
What it funds
How to apply
Read the full announcement on Grants.gov before you start. Federal applications are submitted through Grants.gov (or the agency's own system) and require a Unique Entity ID from SAM.gov. Registration can take several weeks, so start early. Contact: Office of Data Science Strategy (ODSS) · sustainablesoftware@nih.gov · Please contact via email
What are the odds for a first-time applicant?
Mostly repeat grantees: only 8% of awards go to new applicants. Apply with a strong track record or a partner who has won before. Based on 902 new awards in FY2023–25. Organizations under $1M in revenue won 0% of the awards that went to nonprofits. The median award is $866,506. Expect about 101 days between posting and deadline.
Who can apply for Building Sustainable Software Tools for Open Science (R03 Clinical Trial Not Allowed)?
Eligible applicants: 501(c)(3) nonprofits; City or township governments; Private colleges & universities; Federally recognized tribal governments; County governments; State governments; Nonprofits without 501(c)(3) status; Special district governments; For-profit organizations; Public & Indian housing authorities; Native American tribal organizations; Independent school districts; Others (see eligibility text); Small businesses; Public & state-controlled colleges. Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
When is the deadline?
The funder has forecast this opportunity but hasn't announced a deadline yet. Sign up for a reminder and we'll email you when it opens.
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