About this grant
This notice of funding opportunity (NOFO) invites grant applications for the Research Specialist Award (R50) specifically for clinician scientists supporting NCI-funded clinical trials research. The Research Specialist Award is designed to encourage the development of stable research career opportunities for exceptional clinician scientists who want to continue to participate in the NCI clinical trials networks through leadership in the 1) development of national clinical trials, 2) implementation of NCI clinical trials in their institutions, and 3) national service to the NCI clinical trials networks through participation in the scientific review committees, monitoring committees and other activities, but not serve as principal investigators of research project grants. These clinician scientists are vital to sustaining the NCI-funded clinical trials enterprise. The Research Specialist Award is intended to provide salary support and sufficient autonomy so that individuals are not solely dependent on NCI grants held by others or other sources of support for cancer research career continuity.
Who can apply
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
What it funds
How to apply
Read the full announcement on Grants.gov before you start. Federal applications are submitted through Grants.gov (or the agency's own system) and require a Unique Entity ID from SAM.gov. Registration can take several weeks, so start early. Contact: Coordinating Center for Clinical Trials, National Cancer Institute (NCI) · ncir50@mail.nih.gov · Please contact via email
What are the odds for a first-time applicant?
Mostly repeat grantees: only 8% of awards go to new applicants. Apply with a strong track record or a partner who has won before. Based on 52 new awards in FY2023–25. Organizations under $1M in revenue won 0% of the awards that went to nonprofits. The median award is $4,637,432. Expect about 170 days between posting and deadline.
Who can apply for NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)?
Eligible applicants: 501(c)(3) nonprofits; Others (see eligibility text); Native American tribal organizations; County governments; Private colleges & universities; State governments; Small businesses; Special district governments; Independent school districts; Federally recognized tribal governments; For-profit organizations; Public & Indian housing authorities; Nonprofits without 501(c)(3) status; City or township governments; Public & state-controlled colleges. Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
When is the deadline?
Applications are due Nov 2, 2026. Always confirm the time and time zone in the official announcement.
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