Federal · forecast · PAR-27-097 · ALN 93.279

NIDA Core "Center of Transformative Science" Grant Program

National Institutes of Health · HHS

Your odds: program 93.279

Rarely funds nonprofits directly. 86% of awards go to universities and other applicants, so look for a subrecipient or partner role instead.

Based on 1,813 new awards in FY2023–25. Organizations under $1M in revenue won 1% of the awards that went to nonprofits. The median award is $576,936. Expect about 182 days between posting and deadline.

First-time winners
7%
of new 93.279 awards
Nonprofit share
14%
of awards
Median award
$577K
FY2025
New awards, FY2025
516
1,813 in 3 years
Typical window
182 d
usually posts Apr
Under-$1M orgs
1%
of nonprofit awards

Full history for 93.279 Drug Use and Addiction Research Programs: past winners, past rounds, where the money goes

Est. deadline
To be announced
Posted
May 7, 2026
Cost sharing
Not required

About this grant

The National Institute on Drug Abuse (NIDA) seeks to advance its mission by supporting Core Center of Transformative Science Grants. These Centers will bring together investigators currently funded by NIH or other Federal or non-Federal sources to enhance and extend existing research relevant to substance use, addiction, and HIV. Centers are expected to transform the scientific field of study by facilitating research, providing administrative support, and fostering a rigorous research environment that encourages innovative and creative directions. Incremental work should not be the focus of Center activities. Applications responding to this Notice of Funding Opportunity (NOFO) are strongly encouraged to integrate and promote research across funded projects at the applicant institution that align with the Center’s theme, while also supporting interdisciplinary collaborations. Each application should propose a single Center. Centers may include a range of resources with distinct goals across the different scientific areas. They are intended to provide shared resources to a research community, such as imaging capabilities or small-molecule drug chemistry support. Centers must also prioritize providing research opportunities and experiences for new and early-career investigators, facilitating collaborations, and promoting the sharing of data, research findings, and resources to achieve the program goals. Grant authorities that allow NIDA to forecast this opportunity are as follows: 42 U.S.C 241 and 284

Who can apply

State governmentsSmall businessesOthers (see eligibility text)Public & Indian housing authoritiesPrivate colleges & universitiesCounty governments501(c)(3) nonprofitsCity or township governmentsPublic & state-controlled collegesFor-profit organizationsIndependent school districtsSpecial district governmentsNative American tribal organizationsNonprofits without 501(c)(3) statusFederally recognized tribal governments

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

What it funds

How to apply

Read the full announcement on Grants.gov before you start. Federal applications are submitted through Grants.gov (or the agency's own system) and require a Unique Entity ID from SAM.gov. Registration can take several weeks, so start early. Contact: NIDA Referral Officer · NIDAreferral@mail.nih.gov · Please contact via e-mail

View on Grants.gov

What are the odds for a first-time applicant?

Rarely funds nonprofits directly. 86% of awards go to universities and other applicants, so look for a subrecipient or partner role instead. Based on 1,813 new awards in FY2023–25. Organizations under $1M in revenue won 1% of the awards that went to nonprofits. The median award is $576,936. Expect about 182 days between posting and deadline.

Who can apply for NIDA Core "Center of Transformative Science" Grant Program?

Eligible applicants: State governments; Small businesses; Others (see eligibility text); Public & Indian housing authorities; Private colleges & universities; County governments; 501(c)(3) nonprofits; City or township governments; Public & state-controlled colleges; For-profit organizations; Independent school districts; Special district governments; Native American tribal organizations; Nonprofits without 501(c)(3) status; Federally recognized tribal governments. Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

When is the deadline?

The funder has forecast this opportunity but hasn't announced a deadline yet. Sign up for a reminder and we'll email you when it opens.

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