Federal · forecast · PAR-27-117 · ALN 93.T21

INCLUDE Project: Omics Phenotypes Related to Down Syndrome (X01 Clinical Trial Not Allowed)

National Institutes of Health · HHS

Est. deadline
Jun 15, 2027
Posted
Jul 28, 2026
Cost sharing
Not required

About this grant

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to submit samples to NIH INCLUDE Project-supported resources to generate a large volume of integrated genomic and multi-omics data that will facilitate discovery of the molecular mechanisms of health conditions related to Down syndrome. The resulting data, and associated clinical and phenotypic data, will become part of the INCLUDE Data Hub for sharing with the research community. No funding will be provided directly to applicants under this NOFO. Applicants are encouraged to propose omics assays of existing biospecimens collected from individuals with Down syndrome and controls.

Who can apply

Special district governments501(c)(3) nonprofitsPublic & Indian housing authoritiesNonprofits without 501(c)(3) statusIndependent school districtsOthers (see eligibility text)City or township governmentsFederally recognized tribal governmentsPublic & state-controlled collegesSmall businessesNative American tribal organizationsPrivate colleges & universitiesState governmentsCounty governmentsFor-profit organizations

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

What it funds

How to apply

Read the full announcement on Grants.gov before you start. Federal applications are submitted through Grants.gov (or the agency's own system) and require a Unique Entity ID from SAM.gov. Registration can take several weeks, so start early. Contact: The INCLUDE Project · DownSyndromeINCLUDE@mail.nih.gov · Please contact via e-mail.

View on Grants.gov

Who can apply for INCLUDE Project: Omics Phenotypes Related to Down Syndrome (X01 Clinical Trial Not Allowed)?

Eligible applicants: Special district governments; 501(c)(3) nonprofits; Public & Indian housing authorities; Nonprofits without 501(c)(3) status; Independent school districts; Others (see eligibility text); City or township governments; Federally recognized tribal governments; Public & state-controlled colleges; Small businesses; Native American tribal organizations; Private colleges & universities; State governments; County governments; For-profit organizations. Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

When is the deadline?

Applications are due Jun 15, 2027. Always confirm the time and time zone in the official announcement.

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