Single Source Competition for Continuation of Understanding and Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes Clinical Centers (U01 Clinical Trial Not Allowed)

The DISCOVERY of Risk Factors for Type 2 Diabetes in Youth Study is a multi-center longitudinal consortium conducted across 19 clinical sites to identify risk factors and biological mechanisms driving progression to youth-onset type 2 diabetes. The study is actively recruiting and following early pubertal youth at high risk for the disease with longitudinal follow-up currently underway. The current Biostatistics Research Center (BRC) serves as the consortium's central coordinating center, managing protocol implementation, data management, quality assurance, statistical design and analysis, and inter-site and consortium-wide coordination. The BRC has established the robust infrastructure and standardized processes required to support the study and preserve the integrity of the longitudinal dataset. The purpose of this single-source solicitation is to support completion of the scientific objectives of the ongoing DISCOVERY clinical consortium.

This is a Single Source competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Read the full announcement on Grants.gov before you start. Federal applications are submitted through Grants.gov (or the agency's own system) and require a Unique Entity ID from SAM.gov. Registration can take several weeks, so start early. Contact: Division of Diabetes, Endocrinology and Metabolic Diseases · NIDDK_DEM@nih.gov · NIDDK_DEM@nih.gov