Assistance Listing 93.350

National Center for Advancing Translational Sciences

National Institutes of Health · Department of Health and Human Services

The verdict for a small nonprofit

A realistic target for an established nonprofit. 25% of awards go to first-time applicants and nonprofits win 21%.

Based on 341 new awards in FY2023–25. Organizations under $1M in revenue won 0% of the awards that went to nonprofits. The median award is $419,375. Expect about 219 days between posting and deadline.

First-time winners
25%
of new awards, last 3 FYs
Nonprofit share
21%
50% higher ed · 0% gov't
Under-$1M orgs
0%
of nonprofit awards
Median award
$419K
$163K – $2.1M middle half
New awards, FY2025
101
$193M committed to them
Usually posts
Dec
rolling · 219-day window

Open right now under this program

36 opportunities · from Grants.gov, checked every 10 minutes

DeadlineOpportunityExpected awards
Nov 2424 daysCompeting Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)PA-23-317—
Apr 5156 daysNIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102—
Apr 5156 daysNIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100—
May 28209 daysLimited Competition: NCATS Clinical and Translational Science Award (CTSA) Program Research Education Grants Programs (R25 - Clinical Trial Not Allowed)PAR-25-197—
Jul 2244 daysPreclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)RFA-TR-25-002—
Jul 12254 daysChange of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254—
Jul 17259 daysSuccessor-in-Interest (Type 6 Parent Clinical Trial Optional)PA-24-253—
Sep 7311 daysNIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080—
Sep 28332 daysClinical and Translational Science Award (UM1 Clinical Trial Optional)PAR-24-272—
Sep 28332 daysLimited Competition: Mentored Research Career Development Program Award in Clinical and Translational Science Awards (CTSA) Program (K12 Clinical Trial Optional)PAR-25-196—
Sep 28332 daysLimited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)PAR-25-194—
Sep 28332 daysLimited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)PAR-25-195—
Oct 19353 daysLimited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)PAR-25-296—
Nov 16381 daysPilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)PAR-25-122—
Jan 7433 daysNIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)PA-25-301—
Jan 7433 daysNIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)PA-25-304—
Feb 17474 daysExpanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)PAR-25-442—
Jun 15593 daysINCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)RFA-OD-27-004—
Jun 15593 daysINCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research (R61/R33 Clinical Trial Required)RFA-OD-27-005—
Jul 20628 daysClinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)PAR-25-450—
Nov 30761 daysAdministrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)PA-26-001—
Apr 5887 daysNIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)PA-27-101—
Apr 5887 daysSBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)PAR-27-098—
May 7919 daysNIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)PA-26-002—
Forecastdeadline TBALimited Competition: HEAL Initiative Resource Centers for the Pain Management Effectiveness Network (ERN) (Clinical Trial Not Allowed)RFA-TR-26-002—
Forecastdeadline TBALimited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (Clinical Trial Optional)PAR-26-123—
Forecastdeadline TBAIntramural - Extramural Collaboration for Advanced 3-D Tissue Models for Drug Screening (Clinical Trial Not Allowed)RFA-TR-25-0162
Forecastdeadline TBASmall Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039—
Forecastdeadline TBASmall Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040—
Forecastdeadline TBAClinical and Translational Science AwardPAR-28-002—
Forecastdeadline TBALimited Competition: Research Education Program for the Clinical and Translational Science Awards ProgramPAR-28-005—
Forecastdeadline TBALimited Competition: High Impact Specialized Innovation Programs in Clinical and Translational SciencePAR-28-006—
Forecastdeadline TBAThe Next Generation of the Clinical and Translational Science Awards Program Trial Innovation NetworkPAR-28-007—
Forecastdeadline TBALimited Competition: Institutional Mentored Research Career Development Program for the Clinical and Translational Science Awards ProgramPAR-28-003—
Forecastdeadline TBALimited Competition: Clinical and Translational Science Awards (CTSA) Program: Collaborative and Innovative Acceleration AwardPAR-28-008—
Forecastdeadline TBALimited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant for the Clinical and Translational Science Awards ProgramPAR-28-004—

Who won in FY2025

Largest recipients by dollars. From USAspending.

RecipientTypeStateAwardsAwarded
Gordon Research ConferencesNonprofitRI21$420,480
Keystone Symposia on Molecular and Cellular BiologyNonprofitCO16$257,050
The Johns Hopkins UniversityHigher edMD12$59,246,744
Regents of the University of MichiganHigher edMI10$62,063,568
University of North Carolina at Chapel HillHigher edNC10$58,417,055
The Children'S Hospital of PhiladelphiaNonprofitPA10$9,636,999
Icahn School of Medicine at Mount SinaiHigher edNY9$68,306,111
Ohio State University, theHigher edOH9$27,376,888
Virginia Commonwealth UniversityHigher edVA9$25,449,544
University of Pittsburgh - of the Commonwealth System of Higher EducationOtherPA8$41,620,222

New awards by fiscal year

Awards first made in each fiscal year; dollars are the total committed to that year's new awards over their life.

FYNew awardsCommittedMedianMiddle half
2021134$219M$419K$159K – $1.4M
202284$152M$342K$156K – $1.5M
2023122$586M$363K$156K – $3.0M
2024118$306M$431K$169K – $2.1M
2025101$193M$419K$163K – $2.1M

Past rounds

Every announcement under this listing that Grants.gov still lists. Use it to plan next year.

PostedClosedWindowAnnouncement
2026-07-20forecast—PAR-28-002 · Clinical and Translational Science Award
2026-07-20forecast—PAR-28-005 · Limited Competition: Research Education Program for the Clinical and Translational Science Awards Program
2026-07-20forecast—PAR-28-006 · Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science
2026-07-20forecast—PAR-28-007 · The Next Generation of the Clinical and Translational Science Awards Program Trial Innovation Network
2026-07-20forecast—PAR-28-003 · Limited Competition: Institutional Mentored Research Career Development Program for the Clinical and Translational Science Awards Program
2026-07-20forecast—PAR-28-008 · Limited Competition: Clinical and Translational Science Awards (CTSA) Program: Collaborative and Innovative Acceleration Award
2026-07-20forecast—PAR-28-004 · Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant for the Clinical and Translational Science Awards Program
2026-05-282027-04-05312 dPA-27-102 · NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
2026-05-282029-04-051043 dPA-27-101 · NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)
2026-05-282027-04-05312 dPA-27-100 · NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)
2026-05-282029-04-051043 dPAR-27-098 · SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)
2026-05-27forecast—PAR-27-039 · Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)
2026-05-27forecast—PAR-27-040 · Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)
2026-05-132028-06-15764 dRFA-OD-27-005 · INCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research (R61/R33 Clinical Trial Required)
2026-05-122028-06-15765 dRFA-OD-27-004 · INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)
2026-03-09——PAR-26-128 · Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science (RC2 Clinical Trial Optional)
2026-02-18forecast—PAR-26-123 · Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (Clinical Trial Optional)
2026-01-202029-05-071203 dPA-26-002 · NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)
2025-11-262028-11-301100 dPA-26-001 · Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
2025-09-29forecast—RFA-TR-26-002 · Limited Competition: HEAL Initiative Resource Centers for the Pain Management Effectiveness Network (ERN) (Clinical Trial Not Allowed)
2025-09-29forecast—RFA-TR-25-016 · Intramural - Extramural Collaboration for Advanced 3-D Tissue Models for Drug Screening (Clinical Trial Not Allowed)
2025-09-29——RFA-TR-26-001 · Screening for Conditions by Electronic Nose Technology (SCENT III) (Clinical Trial Not Allowed)
2025-09-222028-07-201032 dPAR-25-450 · Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
2025-06-27forecast—FOR-TR-27-002 · Extracellular Vesicle Therapeutics for Regenerative Medicine (ExTReMe)
2025-06-27forecast—FOR-TR-27-003 · Selective Precision Targeting (SPoT)
2025-06-172028-02-17975 dPAR-25-442 · Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)
2025-06-052025-12-09187 dPAR-25-438 · Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)
2024-12-192027-09-281013 dPAR-25-194 · Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)
2024-12-192027-09-281013 dPAR-25-195 · Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)
2024-12-182028-01-071115 dPA-25-301 · NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
2024-12-182028-01-071115 dPA-25-304 · NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)
2024-12-112026-10-19677 dPAR-25-155 · Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)
2024-12-112026-07-16582 dPAR-25-154 · HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)
2024-12-112027-10-191042 dPAR-25-296 · Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)
2024-12-102026-09-28657 dPAR-25-156 · Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science (RC2 Clinical Trials Optional)
2024-12-102026-06-18555 dPAR-25-157 · Awards Supporting Cutting-Edge Technologies for Translational Science (ASCETTS) (R21 Clinical Trials Not Allowed)
2024-12-102027-09-281022 dPAR-25-196 · Limited Competition: Mentored Research Career Development Program Award in Clinical and Translational Science Awards (CTSA) Program (K12 Clinical Trial Optional)
2024-12-092027-05-28900 dPAR-25-197 · Limited Competition: NCATS Clinical and Translational Science Award (CTSA) Program Research Education Grants Programs (R25 - Clinical Trial Not Allowed)
2024-12-062027-07-02938 dRFA-TR-25-002 · Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)
2024-11-202025-12-09384 dPAR-25-217 · Information and Practice Needs Relevant to Late Talking Children (R21 Clinical Trial Not Allowed)

Common questions

How hard is it to win a grant under 93.350?

A realistic target for an established nonprofit. 25% of awards go to first-time applicants and nonprofits win 21%. Based on 341 new awards in FY2023–25. Organizations under $1M in revenue won 0% of the awards that went to nonprofits. The median award is $419,375. Expect about 219 days between posting and deadline.

How much does National Center for Advancing Translational Sciences award?

In FY2025 the median new award was $419K; the middle half ran from $163K to $2.1M. 101 new awards were made, with $193M committed to them.

When does 93.350 usually post?

Over the last several years, new rounds most often posted in Dec with about 219 days to apply. The most recent round posted May 28, 2026.

Who runs this program?

Department of Health and Human Services (National Institutes of Health). Assistance Listing 93.350 on SAM.gov describes the authorizing statute and standard terms.

Sources: USAspending FY2021–25 award archive (2026-10-06); Grants.gov Search2 (fetched 2026-10-28); IRS EO BMF (fetched 2026-10-28). Award counts are new awards by fiscal year of first action. Shares are computed from award counts, not dollars; the under-$1M share covers the 73% of nonprofit awards that matched an IRS revenue record. Recipient type comes from the award record's business-type codes. Always confirm details in the official announcement.

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