Assistance Listing 93.372
21ST Century Cures Act - Brain Research Through Advancing Innovative Neurotechnologies
National Institutes of Health · Department of Health and Human Services
The verdict for a small nonprofit
Rarely funds nonprofits directly. 90% of awards go to universities and other applicants, so look for a subrecipient or partner role instead.
Based on 128 new awards in FY2023–25. Organizations under $1M in revenue won 0% of the awards that went to nonprofits. The median award is $850,780. Expect about 662 days between posting and deadline.
- First-time winners
- 21%
- of new awards, last 3 FYs
- Nonprofit share
- 10%
- 81% higher ed · 0% gov't
- Under-$1M orgs
- 0%
- of nonprofit awards
- Median award
- $851K
- $524K – $2.1M middle half
- New awards, FY2025
- 25
- $40M committed to them
- Usually posts
- Aug
- rolling · 662-day window
Open right now under this program
11 opportunities · from Grants.gov, checked every 10 minutes
Who won in FY2025
Largest recipients by dollars. From USAspending.
| Recipient | Type | State | Awards | Awarded |
|---|---|---|---|---|
| The Leland Stanford Junior University | Higher ed | CA | 11 | $22,558,697 |
| The Trustees of Columbia University in the City of New York | Higher ed | NY | 10 | $5,444,436 |
| The Johns Hopkins University | Higher ed | MD | 9 | $17,730,684 |
| Allen Institute | Nonprofit | WA | 8 | $26,813,412 |
| University of California, San Diego | Higher ed | CA | 7 | $19,812,897 |
| University of California, Los Angeles | Higher ed | CA | 6 | $17,993,088 |
| Regents of the University of California, the | Higher ed | CA | 6 | $15,060,528 |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Other | PA | 6 | $10,820,307 |
| Trustees of the University of Pennsylvania, the | Higher ed | PA | 6 | $9,805,713 |
| University of Texas Health Science Center at Houston | Higher ed | TX | 5 | $19,827,311 |
New awards by fiscal year
Awards first made in each fiscal year; dollars are the total committed to that year's new awards over their life.
| FY | New awards | Committed | Median | Middle half |
|---|---|---|---|---|
| 2021 | 48 | $146M | $2.9M | $211K – $4.8M |
| 2022 | 37 | $72M | $1.5M | $736K – $2.4M |
| 2023 | 72 | $157M | $2.0M | $579K – $3.0M |
| 2024 | 31 | $41M | $498K | $240K – $1.5M |
| 2025 | 25 | $40M | $851K | $524K – $2.1M |
Past rounds
Every announcement under this listing that Grants.gov still lists. Use it to plan next year.
| Posted | Closed | Window | Announcement |
|---|---|---|---|
| 2026-09-30 | 2029-02-08 | 862 d | RFA-NS-28-010 · BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R01 Clinical Trial Not Allowed) |
| 2026-09-10 | forecast | — | RFA-NS-28-006 · BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System |
| 2026-09-10 | forecast | — | RFA-NS-28-005 · Limited Competition: BRAIN Initiative: Promoting Health for All Through BRAIN Technology Partnerships |
| 2026-08-31 | 2028-06-23 | 662 d | RFA-NS-27-002 · BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iBCP (RM1 Clinical Trial Not Allowed) |
| 2026-08-31 | 2028-07-07 | 676 d | PAR-27-076 · Lasker Clinical Research Scholar's Program (Si2/R00 Clinical Trial Optional) |
| 2026-05-28 | 2027-10-04 | 494 d | RFA-NS-27-015 · BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed) |
| 2026-02-09 | 2028-10-06 | 970 d | RFA-NS-27-001 · BRAIN Initiative: Research Resource Grants for Technology Integration and Dissemination (U24 Clinical Trial Not Allowed) |
| 2026-01-26 | forecast | — | RFA-DA-27-011 · BRAIN Initiative: Brain-Behavior Quantification and Synchronization – Transformative Research on Behavior at the Organismal Level |
| 2026-01-20 | 2029-05-07 | 1203 d | PA-26-002 · NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional) |
| 2025-11-26 | 2028-11-30 | 1100 d | PA-26-001 · Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) |
| 2025-09-16 | 2027-11-08 | 783 d | RFA-DA-27-004 · BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed) |
| 2025-05-28 | forecast | — | FOR-NS-25-017 · Small Business Translator: MedTech and Digital Health Technologies |
Common questions
How hard is it to win a grant under 93.372?
Rarely funds nonprofits directly. 90% of awards go to universities and other applicants, so look for a subrecipient or partner role instead. Based on 128 new awards in FY2023–25. Organizations under $1M in revenue won 0% of the awards that went to nonprofits. The median award is $850,780. Expect about 662 days between posting and deadline.
How much does 21ST Century Cures Act - Brain Research Through Advancing Innovative Neurotechnologies award?
In FY2025 the median new award was $851K; the middle half ran from $524K to $2.1M. 25 new awards were made, with $40M committed to them.
When does 93.372 usually post?
Over the last several years, new rounds most often posted in Aug with about 662 days to apply. The most recent round posted Sep 30, 2026.
Who runs this program?
Department of Health and Human Services (National Institutes of Health). Assistance Listing 93.372 on SAM.gov describes the authorizing statute and standard terms.
Sources: USAspending FY2021–25 award archive (2026-10-06); Grants.gov Search2 (fetched 2026-10-28); IRS EO BMF (fetched 2026-10-28). Award counts are new awards by fiscal year of first action. Shares are computed from award counts, not dollars; the under-$1M share covers the 58% of nonprofit awards that matched an IRS revenue record. Recipient type comes from the award record's business-type codes. Always confirm details in the official announcement.