Assistance Listing 93.859

Biomedical Research and Research Training

National Institutes of Health · Department of Health and Human Services

The verdict for a small nonprofit

Rarely funds nonprofits directly. 91% of awards go to universities and other applicants, so look for a subrecipient or partner role instead.

Based on 3,368 new awards in FY2023–25. Organizations under $1M in revenue won 1% of the awards that went to nonprofits. The median award is $781,592. Expect about 307 days between posting and deadline.

First-time winners
5%
of new awards, last 3 FYs
Nonprofit share
9%
80% higher ed · 0% gov't
Under-$1M orgs
1%
of nonprofit awards
Median award
$782K
$429K – $899K middle half
New awards, FY2025
1,008
$844M committed to them
Usually posts
Jun
rolling · 307-day window

Open right now under this program

40 opportunities · from Grants.gov, checked every 10 minutes

DeadlineOpportunityExpected awards
Nov 1010 daysLimited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)RFA-OD-27-009—
Jan 2586 daysTribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T32)PAR-24-235—
Jan 2586 daysTribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T34)PAR-24-236—
Jan 2586 daysMedical Scientist Training Program (MSTP) (T32)PAR-24-128—
Jan 2687 daysNational Centers for Cryo-electron Tomography (cryoET) (R24 -Clinical Trial Not Allowed)PAR-26-138—
Jan 2788 daysBiomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)PAR-24-268—
Jan 2788 daysTribal Institutional Review Board Establishment and Enhancement (TIRBEE) (R24 - Clinical Trial Not Allowed)PAR-24-260—
Feb 9101 daysA Science of Science Approach to Analyzing and Innovating the Biomedical Research Enterprise (SoS:BIO)23-569—
Apr 5156 daysNIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102—
Apr 5156 daysNIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100—
May 7188 daysMentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)PA-24-191—
May 7188 daysMentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185—
May 7188 daysNIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194—
May 8189 daysMentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182—
May 8189 daysMentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184—
Jun 14226 daysNIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed)PAR-25-416—
Jul 12254 daysChange of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254—
Jul 17259 daysSuccessor-in-Interest (Type 6 Parent Clinical Trial Optional)PA-24-253—
Sep 7311 daysNIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080—
Sep 20324 daysJoint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and Mathematical Sciences22-600—
Oct 19353 daysLimited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)PAR-25-296—
Jan 7433 daysFocused Technology Research and Development (R01 Clinical Trial Not Allowed)PAR-25-203—
Jan 7433 daysAcademic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)PAR-25-134—
Jan 7433 daysNIH Research Project Grant (Parent R01 Clinical Trial Required)PA-25-305—
Jan 7433 daysNIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)PA-25-301—
May 4551 daysRuth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)PA-25-168—
May 7554 daysRuth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)PA-25-425—
May 7554 daysRuth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)PA-25-424—
May 7554 daysRuth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)PA-25-423—
May 26573 daysMaximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional)PAR-26-121—
Jul 1609 daysShared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)PAR-27-022—
Jul 7615 daysNative American Research Centers for Health (NARCH) Planning Grants (R34 - Clinical Trial Not Allowed)PAR-25-441—
Sep 7677 daysSupport for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)PAR-25-415—
Sep 7677 daysSupport for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)PAR-25-414—
Sep 25695 daysNIGMS Institutional Biomedical Undergraduate Research Training (BURT) Program (T34)PAR-26-033—
Oct 2702 daysLimited Competition: NIGMS Mature Synchrotron Resources (MSR) for Structural Biology (P30 - Clinical Trial Not Allowed)PAR-27-068—
Nov 30761 daysAdministrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)PA-26-001—
Jan 26818 daysLimited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)PAR-27-067—
Jan 29821 daysBiomedical Technology Optimization and Dissemination Center (BTOD) (RM1 - Clinical Trial Not Allowed)PAR-27-024—
Feb 6829 daysMaximizing Investigators' Research Award (MIRA) for Early Stage Investigators (ESI)PAR-27-032—

Who won in FY2025

Largest recipients by dollars. From USAspending.

RecipientTypeStateAwardsAwarded
Regents of the University of MichiganHigher edMI139$198,851,038
Yale UnivHigher edCT130$206,300,876
The Johns Hopkins UniversityHigher edMD119$208,163,796
University of California, San DiegoHigher edCA117$215,611,666
Regents of the University of California, San Francisco, theHigher edCA117$177,263,599
The Leland Stanford Junior UniversityHigher edCA111$243,822,973
University of Wisconsin SystemHigher edWI110$195,118,263
Regents of the University of California, theHigher edCA109$148,976,179
The University of ChicagoHigher edIL99$173,685,678
The University of Texas Southwestern Medical CenterHigher edTX94$152,092,146

New awards by fiscal year

Awards first made in each fiscal year; dollars are the total committed to that year's new awards over their life.

FYNew awardsCommittedMedianMiddle half
20212,665$4.6B$1.4M$390K – $2.2M
20221,508$2.7B$1.6M$570K – $2.1M
20231,274$1.8B$1.4M$543K – $1.7M
20241,086$1.2B$1.1M$402K – $1.2M
20251,008$844M$782K$429K – $899K

Past rounds

Every announcement under this listing that Grants.gov still lists. Use it to plan next year.

PostedClosedWindowAnnouncement
2026-10-142029-09-261078 dPAR-27-003 · Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional)
2026-09-242026-11-1047 dRFA-OD-27-009 · Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)
2026-09-16forecast—PAR-29-005 · Technology Development Program
2026-09-14forecast—PAR-28-050 · Limited Competition: Tribal Undergraduate and Graduate Research Training and Leadership Experiences (TURTLE) Program
2026-09-14forecast—PAR-28-038 · Limited Competition: Tribal Institutional Review Board Establishment and Enhancement (TIRBEE)
2026-08-312028-10-02763 dPAR-27-068 · Limited Competition: NIGMS Mature Synchrotron Resources (MSR) for Structural Biology (P30 - Clinical Trial Not Allowed)
2026-08-192029-05-301015 dPAR-27-056 · Limited Competition: Institutional Development Award (IDeA) for Clinical & Translational Research (CTR) (P30 - CT Optional)
2026-08-192029-05-261011 dPAR-27-054 · Limited Competition: Centers of Biomedical Research Excellence: Development Phase (COBRE-D) (P30 - Clinical Trial Not Allowed)
2026-07-30forecast—PAR-28-037 · Investigator-Focused Award (Parent R35)
2026-06-252028-07-01737 dPAR-27-022 · Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)
2026-06-222029-07-121116 dPA-27-030 · Institutional Mentored Career Development Award (Parent K12) (Clinical Trials Not Allowed)
2026-06-182029-05-251072 dPAR-27-055 · Limited Competition: Centers of Biomedical Research Excellence: Expansion/Sustainability Phases (COBRE-E/S) (P30 - Clinical Trial Not Allowed)
2026-06-162029-04-081027 dPA-27-037 · Predoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed)
2026-06-082029-05-251082 dPA-27-034 · NIH Research Education Program - Courses, Curriculum & Methods (Parent R25 - Clinical Trial Not Allowed)
2026-06-082029-05-051062 dPA-27-035 · NIH Research Educational Program - Mentoring Activities & Networks (Parent R25/UE5 - Clinical Trial Not Allowed)
2026-06-082029-01-29966 dPAR-27-024 · Biomedical Technology Optimization and Dissemination Center (BTOD) (RM1 - Clinical Trial Not Allowed)
2026-06-082029-05-051062 dPA-27-036 · NIH Research Education Program - Research Experiences (Parent R25 - Clinical Trial Not Allowed)
2026-05-282027-04-05312 dPA-27-102 · NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
2026-05-282029-04-051043 dPA-27-101 · NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)
2026-05-282027-04-05312 dPA-27-100 · NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)
2026-05-282029-04-051043 dPAR-27-098 · SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)
2026-05-27forecast—PAR-27-039 · Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)
2026-05-27forecast—PAR-27-040 · Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)
2026-05-272029-01-26975 dPAR-27-067 · Limited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)
2026-05-27forecast—PAR-28-024 · Single Source: Institutional Development Award (IDeA) Clinical Research Resource Center (I-CRRC)
2026-05-27forecast—PAR-28-025 · Single Source: Resource Center for the Support for Research Excellence (SuRE) Program
2026-05-26forecast—PAR-29-004 · Limited Competition: Biomedical Research Environment & Sponsored Programs Administration Development (BRE-SPAD) Program
2026-05-122029-02-061001 dPAR-27-032 · Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI)
2026-05-052029-05-251116 dPAR-27-077 · NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed)
2026-02-10forecast—PAR-27-002 · Medical Scientist Training Program (MSTP)
2026-02-10forecast—PAR-27-001 · Native American Research Centers for Health (NARCH)
2026-02-052027-01-26355 dPAR-26-138 · National Centers for Cryo-electron Tomography (cryoET) (R24 -Clinical Trial Not Allowed)
2026-01-202029-05-071203 dPA-26-002 · NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)
2025-12-292028-09-251001 dPAR-26-033 · NIGMS Institutional Biomedical Undergraduate Research Training (BURT) Program (T34)
2025-12-112028-05-26897 dPAR-26-121 · Maximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional)
2025-11-262028-11-301100 dPA-26-001 · Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
2025-09-22forecast—PAR-26-026 · IDeA Networks of Biomedical Research Excellence (INBRE)
2025-08-262028-07-071046 dPAR-25-441 · Native American Research Centers for Health (NARCH) Planning Grants (R34 - Clinical Trial Not Allowed)
2025-06-132028-09-071182 dPAR-25-415 · Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)
2025-06-132028-09-071182 dPAR-25-414 · Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)

Common questions

How hard is it to win a grant under 93.859?

Rarely funds nonprofits directly. 91% of awards go to universities and other applicants, so look for a subrecipient or partner role instead. Based on 3,368 new awards in FY2023–25. Organizations under $1M in revenue won 1% of the awards that went to nonprofits. The median award is $781,592. Expect about 307 days between posting and deadline.

How much does Biomedical Research and Research Training award?

In FY2025 the median new award was $782K; the middle half ran from $429K to $899K. 1,008 new awards were made, with $844M committed to them.

When does 93.859 usually post?

Over the last several years, new rounds most often posted in Jun with about 307 days to apply. The most recent round posted Oct 14, 2026.

Who runs this program?

Department of Health and Human Services (National Institutes of Health). Assistance Listing 93.859 on SAM.gov describes the authorizing statute and standard terms.

Sources: USAspending FY2021–25 award archive (2026-10-06); Grants.gov Search2 (fetched 2026-10-28); IRS EO BMF (fetched 2026-10-28). Award counts are new awards by fiscal year of first action. Shares are computed from award counts, not dollars; the under-$1M share covers the 69% of nonprofit awards that matched an IRS revenue record. Recipient type comes from the award record's business-type codes. Always confirm details in the official announcement.

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