About this grant
The Biomedical Research Environment & Sponsored Programs Administration Development (BRE-SPAD) Program supports resource-limited institutions to develop and strengthen their capacity to conduct rigorous and reproducible biomedical research. Eligible organizations are expected to propose plans based on identified needs in one or more of the following areas: biomedical research environment, sponsored programs administration and a post-award pilot research project program. By supporting research capacity building at resource-limited institutions, the BRE-SPAD program will expand and strengthen the pool of faculty and trainees conducting rigorous biomedical research, and the organizational settings where NIH-funded research is performed. This is a Forecast for a Limited Competition that will invite applications from eligible organizations to apply. Please see the Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered for funding.
Who can apply
The following applicants are eligible:Historically Black College or University (HBCU) (see 20 U.S.C. 1061(2)), ORTribal entity defined as:A federally recognized AI/AN Tribe, as defined under 25 U.S.C. 1603(14); orA Tribal college or university, a Tribal health program, or a Tribal organization as defined under 25 U.S.C. 1603 (24), (25), and (26), respectively; orA consortium of two or more of those Tribal entities, ORResource-limited institutions with limited NIH Research Project Grant Funding
What it funds
How to apply
Read the full announcement on Grants.gov before you start. Federal applications are submitted through Grants.gov (or the agency's own system) and require a Unique Entity ID from SAM.gov. Registration can take several weeks, so start early. Contact: NIGMS BRE-SPAD Program Contacts · NIGMSBRE-SPAD@nigms.nih.gov · Please contact via email.
What are the odds for a first-time applicant?
Rarely funds nonprofits directly. 91% of awards go to universities and other applicants, so look for a subrecipient or partner role instead. Based on 3,368 new awards in FY2023–25. Organizations under $1M in revenue won 1% of the awards that went to nonprofits. The median award is $781,592. Expect about 307 days between posting and deadline.
Who can apply for Limited Competition: Biomedical Research Environment & Sponsored Programs Administration Development (BRE-SPAD) Program?
Eligible applicants: Federally recognized tribal governments; 501(c)(3) nonprofits; Nonprofits without 501(c)(3) status; Private colleges & universities; Native American tribal organizations; Public & state-controlled colleges. The following applicants are eligible:Historically Black College or University (HBCU) (see 20 U.S.C. 1061(2)), ORTribal entity defined as:A federally recognized AI/AN Tribe, as defined under 25 U.S.C. 1603(14); orA Tribal college or university, a Tribal health program, or a Tribal organization as defined under 25 U.S.C. 1603 (24), (25), and (26), respectively; orA consortium of two or more of thos
When is the deadline?
Applications are due Jan 27, 2028. Always confirm the time and time zone in the official announcement.
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